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S-ence

S-ence

Regular price $190.00
Regular price $213.00 Sale price $190.00
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Description

The Science Behind This Formula

S-ence is an all-in-one formula that replaces a multi-step routine. It combines microcollagen (low molecular weight collagen engineered to penetrate the stratum corneum), green algae extract (stimulates glycosaminoglycan synthesis for skin plumpness), and a peptide complex — all delivered through a phospholipid carrier system. The challenge that took five years: making all of these work simultaneously in an organic-certified base at therapeutic concentrations.

Ingredient comparison chart

Development Timeline

5 years of development — the same cycle as Le Serum, applied to a broader multi-active system.

Key Ingredient Breakdown

Ingredient Function Why Concentration Matters
Microcollagen Low molecular weight collagen that reaches the viable epidermis to support the natural collagen matrix Engineered for depth — most collagen in skincare is too large to penetrate
Green Algae Extract Stimulates glycosaminoglycan synthesis, supporting skin plumpness and structure Concentrated bioactive extract, not dried powdered algae
Phospholipid Delivery System Biocompatible carrier for simultaneous delivery of multiple active ingredients Same technology used in Le Serum, adapted for broader spectrum

What Makes This Cosmeceutical-Grade

Penetrating base. The formula is engineered with a delivery system designed to carry active ingredients beyond the stratum corneum to the viable epidermis, where living cells respond.

Oregon Tilth certified organic. One of the strictest organic certifications in the United States — achieved at therapeutic active concentrations, which most organic-certified brands cannot maintain.

FDA-registered manufacturing. The facility meets federal standards for drug-licensed production, a higher bar than cosmetic-only manufacturing.

Formulated by PhD scientists. Dr. Volynsky (PhD organic chemistry) and Dr. Libaridian (PhD pharmaceuticals, R.Ph.) with a combined 50+ years of formulation research.

Learn More About Science | About our founders | Doctor's Notes blog

What S-ence Replaces

S-ence is not an addition to your routine. It is a replacement for multiple steps — a single product that does the work of a serum, a moisturiser, and a treatment.

This is not a shortcut. It is a different approach to formulation: instead of distributing active ingredients across multiple bottles with potentially conflicting pH levels and delivery requirements, S-ence combines them in a single phospholipid-based system that determines the release rate and depth for each active independently.

The Problem with Multi-Step Routines

A typical anti-aging routine involves four to six products: cleanser, toner, serum, eye cream, moisturiser, and occasional treatment. Each product has its own pH. Each active ingredient has its own stability requirements. Some ingredients compete for the same skin receptors. Others neutralise each other on contact.

The result is a routine where the products are often working against each other — and the user is spending more time managing the routine than benefiting from it.

S-ence solves this by engineering a single formula where every active was designed to work with every other active from the start.

Key Ingredients

Ingredient Comparison: Conventional vs S-ence

Ingredient Conventional Skincare S-ence (Cosmeceutical)
Collagen type High MW (too large to penetrate) Microcollagen — low MW (reaches viable epidermis)
Delivery vehicle Standard cream base Phospholipid carrier
Algae ingredient Dried or powdered (minimal bioactivity) Green Algae extract (stimulates GAG synthesis)
Development 6-12 months 5 years

Phospholipid delivery diagram

Microcollagen — collagen at a molecular weight small enough to penetrate the stratum corneum and reach the viable epidermis, where it supports the skin's natural collagen matrix. Most collagen in skincare is too large to penetrate; it sits on the surface and hydrates. Microcollagen is engineered for depth.

Green Algae Extract — stimulates glycosaminoglycan synthesis, supporting the skin's natural plumpness and structure. It also stabilises the collagen stimulation response, preventing the overstimulation that can occur when collagen-supporting ingredients are used in isolation.

Peptide Complex — provides the signalling molecules that tell skin cells to maintain their function, supporting texture, firmness, and resilience over time.

Phospholipid Delivery System — the same technology used in Le Serum, adapted for a broader spectrum of actives. Phospholipids are biocompatible — they are the same class of molecules that make up human cell membranes — allowing them to ferry active ingredients across biological barriers without triggering an immune response.

The Development

S-ence took five years. The challenge was not formulating the individual ingredients — each of microcollagen, green algae extract, and the peptide complex is well-characterised on its own. The challenge was making all of them work simultaneously in an organic-certified base, at therapeutic concentrations, with clinical stability, in a single product that replaces four to six separate bottles.

The Economics

A typical premium anti-aging regimen costs $200–$400 per month when you add up serum, moisturiser, eye cream, and treatment products. S-ence costs significantly less than the sum of products it replaces — because one formula costs less to develop, manufacture, and package than four.

Usage

Apply a small amount to clean, dry skin morning and evening. Use over the entire face, neck, and décolletage. No additional serum, moisturiser, or treatment needed. Follow with SPF in the morning.

Comparison

Ultra-luxe prestige skincare luxury brands charge $385 for a single cream formulated around a proprietary fermentation technology. S-ence has comparable formulation complexity — multiple active ingredients, a bioavailable delivery system, organic certification, five years of development — at a fraction of the price. The formulation budget is allocated to ingredient concentration and delivery technology, not advertising.

Suitable For

  • Simplified anti-aging routines — one product instead of four to six
  • Mature skin needing broad-spectrum multi-active support
  • Those who prefer a single-step day/night product for consistency
  • Travel and low-maintenance routines

Directions

Apply twice daily on entire face, around the eyes, neck, and decollete.

Key Ingredients

  1. Peptide (Palmitoyl Pentapeptide-3): The major ingredient that promotes collagen and hyaluronic acid production. This will stimulate the skin to produce collagen and recover normally, thus rejuvenating the skin and reducing the presence of wrinkles or fine lines.
  2. Algae Extract: Plays a crucial role in skin nourishment and hydration.
  3. Vitamin E: Essential nutrient and antioxidant that provides excellent skin protection to maintain overall health.
  4. Beta-Carotene: Antioxidant that contains various skin benefits, such as brightened skin tone, increased skin cell turnover, and photoprotection.

All Ingredients

  • Aqua
  • Palmitoyl pentapeptide-3
  • Petrolatum
  • Glycerin
  • Hydrogenated polyisobutene
  • Cyclopentasiloxane
  • Polyethylene
  • PEG/PPG-20/50 dimethicone
  • Phenyl methicone
  • Squalane
  • Propene glycol
  • Sodium PCA
  • Algae extract
  • Sodium acrylates copolymer
  • Lecithin
  • Polyglyceryl-10 stearate
  • Ceresin
  • Paraffinum liquidum
  • Phenoxyethanol
  • Caprylyl glycol
  • Isopentyldiol
  • Allantoin
  • Tocopherol
  • Beta-carotene fragrance

Suitable for

SKIN ELASTICITY

  • COMPLIMENTARY GIFT WHEN YOU SPEND $300+

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DISCOVER ALL-IN-ONE SOLUTION

All-in-one skin repair system that can rejuvenate the skin around your eyes, neck, and entire face.

A rich day and night cream that can refresh the skin and give you the fresh, glowing appearance you deserve. It’s made with green algae extract to help stimulate glycosaminoglycans synthesis and collagen production, both of which plump the skin and reduce wrinkles.

FREQUENTLY ASKED QUESTIONS

Can I use the S-Ence Cream if I have dry skin?

Yes, you can! The cream is suitable for all skin types, including dry skin. In fact, it is helpful for dry and dehydrated skin as it contains phospholipids, which results in long-lasting skin hydration.

Does the S-Ence Cream offer anti-aging benefits?

Yes, S-Ence is formulated with vitamins and other essential ingredients that correct age-related skin changes and improve sagging skin.

How does S-Ence help with anti-aging?

The S-Ence day and night cream offers micro-collagen and green algae extract, which stimulates collagen and glycosaminoglycans synthesis. As a result, the cream can re-plump your skin and reduce wrinkles.