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Pluripotential Cream

Pluripotential Cream

Regular price $115.00
Regular price Sale price $115.00
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Size

Description

The Science Behind This Formula

Pluripotencial uses the same Argireline (acetyl hexapeptide-8) active found in Le Serum, delivered through the same phospholipid penetrating base. The difference is the formulation: a richer cream base that provides sustained hydration alongside the anti-wrinkle mechanism, making it a complete single-step product. The same core technology — the same neuromuscular modulation — now accessible in a daily-use cream.

Ingredient comparison chart

Development Timeline

Same 5-year development cycle as Le Serum — the core Argireline technology and delivery system are identical.

Key Ingredient Breakdown

Ingredient Function Why Concentration Matters
Argireline (Acetyl Hexapeptide-8) Neuromuscular modulation — same pathway as injectables, topical application 10% therapeutic concentration in a penetrating base
Rich cream base Provides sustained moisture and barrier support alongside the active peptide Eliminates need for separate serum and moisturiser in the routine

What Makes This Cosmeceutical-Grade

Penetrating base. The formula is engineered with a delivery system designed to carry active ingredients beyond the stratum corneum to the viable epidermis, where living cells respond.

Oregon Tilth certified organic. One of the strictest organic certifications in the United States — achieved at therapeutic active concentrations, which most organic-certified brands cannot maintain.

FDA-registered manufacturing. The facility meets federal standards for drug-licensed production, a higher bar than cosmetic-only manufacturing.

Formulated by PhD scientists. Dr. Volynsky (PhD organic chemistry) and Dr. Libaridian (PhD pharmaceuticals, R.Ph.) with a combined 50+ years of formulation research.

Learn More About Science | About our founders | Doctor's Notes blog

The Same Science. The Same Mechanism. More Accessible.

Not every luxury needs a luxury price.

Pluripotencial delivers the core Argireline neuropeptide technology in Dr. Volynsky's penetrating base — the same fundamental approach as Le Serum, formulated as a richer cream for everyday use.

How It Works

Pluripotencial uses the same Argireline (acetyl hexapeptide-8) active ingredient found in Le Serum, delivered through the same phospholipid-based penetrating system. The peptide modulates neurotransmitter release at the neuromuscular junction, reducing the micro-contractions that form expression lines.

The difference is the base: Pluripotencial is formulated as a complete cream rather than a concentrated serum, providing sustained hydration and barrier support alongside the anti-wrinkle mechanism. This makes it ideal for those who prefer a single-step product or whose skin benefits from a richer formulation.

Positioning

Think of it as the accessible counterpart to Le Serum. Same engineering philosophy. Same core technology. Same rigorous formulation standards. Different tier — designed to make the science accessible to more people.

Pluripotencial is not a "budget version." It is a different expression of the same technology, built for daily, consistent use.

Usage

Apply a pea-sized amount to clean, dry skin morning and evening. Focus on the forehead, eye area, and between the brows. Use as your moisturiser step — no additional cream needed. Follow with SPF in the morning.

Suitable For

  • Those who want Argireline benefits in a richer, all-in-one cream
  • Dry, dehydrated, or mature skin that needs sustained moisture
  • Simplified routines — one product instead of serum plus moisturiser
  • Anyone seeking an entry point into peptide-based anti-wrinkle care

Also Consider

Le Serum — the full therapeutic formulation at maximum concentration. Five years of development. For those who want no compromises in their anti-wrinkle regimen.

Directions

Apply to clean skin twice a day.

Key Ingredients

  1. Peptides: Promotes collagen production, which helps with skin repair, firmness, and reducing
    wrinkles.
  2. Vitamins A and E: Essential vitamins that contribute to improving skin health and reducing
    wrinkles, especially shallow to medium-depth wrinkles.
  3. Long-lasting water preservation: Supports synergy between the dermal matrix and fibroblasts,stimulating collagen fibers to firm the skin.

All Ingredients

  • Aqua
  • Glycerin
  • Caprylic/capric triglyceride
  • Cetearyl alcohol
  • Ceteareth 20
  • C12-15 alkyl benzoate
  • Pentaerythrityl tetraoctanoate
  • PPG-12/SMDl copolymer
  • Behenyl alcohol
  • Glyceryl stearate
  • PEG-100 stearate
  • Sodium hyaluronate
  • C 10-30 cholesterol/lanosterol esters
  • Squalane
  • Hydrogenated palm glycerides
  • Phenoxyethanol
  • Caprylyl glycol
  • Isopentyldiol
  • Carbomer
  • Octyldodecanol
  • Allantoin
  • Triethanolamine
  • Palmitoyl pentapeptide-3
  • Dipalmitoyl hydroxyproline
  • Parfum
  • Tetrasodium EDTA
  • Tocopheryl acetate
  • Retinyl palmitate
  • Silica

Suitable for

REDNESS

POLLUTION PROTECTION

ACNE

  • COMPLIMENTARY GIFT WHEN YOU SPEND $300+

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DISCOVER ALL-IN-ONE SOLUTION

All-in-one skin repair system that can rejuvenate the skin around your eyes, neck, and entire face.

A rich day and night cream that can refresh the skin and give you the fresh, glowing appearance you deserve. It’s made with green algae extract to help stimulate glycosaminoglycans synthesis and collagen production, both of which plump the skin and reduce wrinkles.

FREQUENTLY ASKED QUESTIONS

What type of anti-aging benefits can I expect from the Pluripotential Cream?

This multifunctional cream offers numerous benefits when used consistently, such as restoring firmer skin, reducing wrinkles, improving skin repair, and providing ultimate hydration.

What is the Pluripotential Cream made of?

The Nujevi Pluripotential Cream is made of numerous key ingredients that help give you younger-looking skin, including peptides, and vitamins A and E. These are made to promote collagen production and improve overall skin health.

How many times a day should I use the Pluripotential Cream?

You should apply this onto clean skin twice a day, once in the morning and once before going to bed.