Phytic Treatment Concentrate
What Is Phytic Acid?

Phytic acid is a naturally occurring antioxidant derived from brown rice (rice bran). It belongs to a class of compounds known as inositol phosphates and has been studied for its ability to chelate metals, inhibit melanin production, and provide antioxidant protection at the cellular level.
In cosmeceutical applications, phytic acid offers a fundamentally different mechanism than conventional chemical exfoliants. It is not a simple acid peel. It is a multi-pathway active that addresses pigmentation, antioxidant protection, and skin remodelling simultaneously.
The Clinical Comparison: Phytic vs. Glycolic Acid

The most widely used chemical exfoliant in professional settings is glycolic acid, typically at concentrations of 30–70%. It is effective — but it is also cytotoxic at therapeutic concentrations.
Phytic acid has been clinically evaluated against 50% glycolic acid at 15 minutes of contact time. The results:
- Equivalent efficacy — phytic acid achieved comparable results to 50% glycolic acid for skin resurfacing within the same time window
- No cytotoxicity — glycolic acid at 50% is cytotoxic (damages living cells). Phytic acid showed no cytotoxic effects at equivalent contact time
- Cell proliferation confirmed — Ki-67 staining, a standard marker for cell proliferation, confirmed that skin cells continued to divide and function normally under phytic acid treatment
This means phytic acid can achieve the same clinical outcome as a high-concentration glycolic peel — without the tissue damage that requires professional oversight and extended recovery time.
Tyrosinase Inhibition
Phytic acid also inhibits tyrosinase, the enzyme responsible for melanin production, at levels comparable to Kojic acid — one of the most widely used skin-lightening agents in dermatology.
This makes it relevant for:
- Hyperpigmentation and melasma treatment
- Post-inflammatory hyperpigmentation from acne
- Sun damage and uneven skin tone
- Maintenance after professional pigmentation treatments
The advantage over Kojic acid: phytic acid provides both tyrosinase inhibition and chemical exfoliation in a single mechanism, without the stability issues that make Kojic acid challenging to formulate.
Current Use in Our Products
Phytic acid is currently formulated into our cleanser, where it provides gentle exfoliation and brightening benefits as part of a daily cleansing routine. It is also a key active in our Spot Corrector and Toner.
Available for Professional Use
MD Cosmetique's Phytic Treatment Concentrate is a professional-grade formulation of phytic acid for use in clinical and spa settings. If you are a licensed esthetician, dermatologist, or spa professional, contact us about professional access. [Contact link]
