{"title":"Dry \u0026 Dehydrated Skin","description":"\u003ch2\u003eDeep Hydration and Barrier Support\u003c\/h2\u003e\u003cp\u003eProducts formulated to restore moisture balance and strengthen the skin barrier — essential for dry, dehydrated, or climate-stressed skin.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eHow to choose:\u003c\/strong\u003e S-ence provides comprehensive hydration plus anti-aging actives in one step. For targeted hydration, our Hyaluronic Acid products deliver multi-weight moisture. Hand Foot and Elbow Cream provides intensive repair for very dry areas.\u003c\/p\u003e","products":[{"product_id":"hand-foot-elbow-cream","title":"Hand Foot and Elbow Cream","description":"\u003ch2\u003eThe Science Behind This Formula\u003c\/h2\u003e\n\u003cp\u003eFormulated to form a thin protective layer that locks in moisture for 7-9 hours, supporting barrier repair in high-stress skin areas.\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"placeholder_comparison_chart.png\" alt=\"Ingredient comparison chart\" style=\"width:100%;max-width:700px;margin:20px 0;\"\u003e\u003c\/p\u003e\n\u003ch3\u003eDevelopment Timeline\u003c\/h3\u003e\n\u003cp\u003eFormulated for intensive barrier support in thick-skin areas.\u003c\/p\u003e\n\n\u003ch3\u003eKey Ingredient Breakdown\u003c\/h3\u003e\n\u003ctable style=\"width:100%;max-width:700px;border-collapse:collapse;margin:20px 0;font-family:Assistant,Arial,sans-serif;font-size:14px;\"\u003e\n  \u003cthead\u003e\n    \u003ctr style=\"background:#f5f5f5;color:#333;font-weight:600;\"\u003e\n      \u003cth style=\"padding:12px;text-align:left;border:1px solid #ddd;\"\u003eIngredient\u003c\/th\u003e\n      \u003cth style=\"padding:12px;text-align:left;border:1px solid #ddd;\"\u003eFunction\u003c\/th\u003e\n      \u003cth style=\"padding:12px;text-align:center;border:1px solid #ddd;\"\u003eWhy Concentration Matters\u003c\/th\u003e\n    \u003c\/tr\u003e\n  \u003c\/thead\u003e\n  \u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding:10px;border:1px solid #ddd;font-weight:600;\"\u003eLong-Lasting Moisture Barrier\u003c\/td\u003e\n\u003ctd style=\"padding:10px;border:1px solid #ddd;\"\u003eProtective layer locks in moisture for 7-9 hours\u003c\/td\u003e\n\u003ctd style=\"padding:10px;border:1px solid #ddd;text-align:center;\"\u003eFragrance-free, suitable for frequent application\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\n\u003ch3\u003eWhat Makes This Cosmeceutical-Grade\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003ePenetrating base.\u003c\/strong\u003e The formula is engineered with a delivery system designed to carry active ingredients beyond the stratum corneum to the viable epidermis, where living cells respond.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOregon Tilth certified organic.\u003c\/strong\u003e One of the strictest organic certifications in the United States — achieved at therapeutic active concentrations, which most organic-certified brands cannot maintain.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFDA-registered manufacturing.\u003c\/strong\u003e The facility meets federal standards for drug-licensed production, a higher bar than cosmetic-only manufacturing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFormulated by PhD scientists.\u003c\/strong\u003e Dr. Volynsky (PhD organic chemistry) and Dr. Libaridian (PhD pharmaceuticals, R.Ph.) with a combined 50+ years of formulation research.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/pages\/science-v2\"\u003eLearn More About Science\u003c\/a\u003e | \u003ca href=\"\/pages\/about-us\"\u003eAbout our founders\u003c\/a\u003e | \u003ca href=\"\/blogs\/doctor-notes\"\u003eDoctor's Notes blog\u003c\/a\u003e\u003c\/p\u003e\n","brand":"CRC","offers":[{"title":"16 oz (480 g)","offer_id":48495143158080,"sku":"HFE-16","price":180.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0828\/2328\/3008\/files\/IMG_2577.jpg?v=1708609753"},{"product_id":"hyaluronic-acid","title":"Hyaluronic Acid","description":"\u003ch2\u003eThe Science Behind This Formula\u003c\/h2\u003e\n\u003cp\u003eThe Nujevi Hyaluronic Acid serum uses multi-molecular-weight HA: high molecular weight for immediate surface hydration and plumping, low molecular weight for deeper sustained hydration. HA can hold up to 1,000 times its weight in water.\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"placeholder_comparison_chart.png\" alt=\"Ingredient comparison chart\" style=\"width:100%;max-width:700px;margin:20px 0;\"\u003e\u003c\/p\u003e\n\u003ch3\u003eDevelopment Timeline\u003c\/h3\u003e\n\u003cp\u003eFormulated with dual MW HA technology for immediate and cumulative hydration.\u003c\/p\u003e\n\n\u003ch3\u003eKey Ingredient Breakdown\u003c\/h3\u003e\n\u003ctable style=\"width:100%;max-width:700px;border-collapse:collapse;margin:20px 0;font-family:Assistant,Arial,sans-serif;font-size:14px;\"\u003e\n  \u003cthead\u003e\n    \u003ctr style=\"background:#f5f5f5;color:#333;font-weight:600;\"\u003e\n      \u003cth style=\"padding:12px;text-align:left;border:1px solid #ddd;\"\u003eIngredient\u003c\/th\u003e\n      \u003cth style=\"padding:12px;text-align:left;border:1px solid #ddd;\"\u003eFunction\u003c\/th\u003e\n      \u003cth style=\"padding:12px;text-align:center;border:1px solid #ddd;\"\u003eWhy Concentration Matters\u003c\/th\u003e\n    \u003c\/tr\u003e\n  \u003c\/thead\u003e\n  \u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding:10px;border:1px solid #ddd;font-weight:600;\"\u003eHigh MW Hyaluronic Acid\u003c\/td\u003e\n\u003ctd style=\"padding:10px;border:1px solid #ddd;\"\u003eImmediate surface hydration and visible plumping\u003c\/td\u003e\n\u003ctd style=\"padding:10px;border:1px solid #ddd;text-align:center;\"\u003eBoth MWs present simultaneously — uncommon in conventional HA serums\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding:10px;border:1px solid #ddd;font-weight:600;\"\u003eLow MW Hyaluronic Acid\u003c\/td\u003e\n\u003ctd style=\"padding:10px;border:1px solid #ddd;\"\u003ePenetrates deeper for sustained hydration and structural support\u003c\/td\u003e\n\u003ctd style=\"padding:10px;border:1px solid #ddd;text-align:center;\"\u003eRequires additional stabilisation; more expensive to produce\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\n\u003ch3\u003eWhat Makes This Cosmeceutical-Grade\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003ePenetrating base.\u003c\/strong\u003e The formula is engineered with a delivery system designed to carry active ingredients beyond the stratum corneum to the viable epidermis, where living cells respond.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOregon Tilth certified organic.\u003c\/strong\u003e One of the strictest organic certifications in the United States — achieved at therapeutic active concentrations, which most organic-certified brands cannot maintain.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFDA-registered manufacturing.\u003c\/strong\u003e The facility meets federal standards for drug-licensed production, a higher bar than cosmetic-only manufacturing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFormulated by PhD scientists.\u003c\/strong\u003e Dr. Volynsky (PhD organic chemistry) and Dr. Libaridian (PhD pharmaceuticals, R.Ph.) with a combined 50+ years of formulation research.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/pages\/science-v2\"\u003eLearn More About Science\u003c\/a\u003e | \u003ca href=\"\/pages\/about-us\"\u003eAbout our founders\u003c\/a\u003e | \u003ca href=\"\/blogs\/doctor-notes\"\u003eDoctor's Notes blog\u003c\/a\u003e\u003c\/p\u003e\n","brand":"Nujevi","offers":[{"title":"1 fl oz (30 ml)","offer_id":48495146500416,"sku":"HYAC","price":72.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0828\/2328\/3008\/files\/mdcosmetique-nujevi-hyaluronic-acid.webp?v=1715716050"},{"product_id":"s-ence","title":"S-ence","description":"\u003ch2\u003eThe Science Behind This Formula\u003c\/h2\u003e\n\u003cp\u003eS-ence is an all-in-one formula that replaces a multi-step routine. It combines microcollagen (low molecular weight collagen engineered to penetrate the stratum corneum), green algae extract (stimulates glycosaminoglycan synthesis for skin plumpness), and a peptide complex — all delivered through a phospholipid carrier system. The challenge that took five years: making all of these work simultaneously in an organic-certified base at therapeutic concentrations.\u003c\/p\u003e\n\u003cp\u003e\u003cimg alt=\"Ingredient comparison chart\" style=\"width: 100%; max-width: 700px; margin: 20px 0;\"\u003e\u003c\/p\u003e\n\u003ch3\u003eDevelopment Timeline\u003c\/h3\u003e\n\u003cp\u003e5 years of development — the same cycle as Le Serum, applied to a broader multi-active system.\u003c\/p\u003e\n\u003ch3\u003eKey Ingredient Breakdown\u003c\/h3\u003e\n\u003ctable style=\"width: 100%; max-width: 700px; border-collapse: collapse; margin: 20px 0; font-family: Assistant,Arial,sans-serif; font-size: 14px;\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"background: #1a2b4a; color: #fff;\"\u003e\n\u003cth style=\"padding: 12px; text-align: left; border: 1px solid #ddd;\"\u003eIngredient\u003c\/th\u003e\n\u003cth style=\"padding: 12px; text-align: left; border: 1px solid #ddd;\"\u003eFunction\u003c\/th\u003e\n\u003cth style=\"padding: 12px; text-align: center; border: 1px solid #ddd;\"\u003eWhy Concentration Matters\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; font-weight: 600;\"\u003eMicrocollagen\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd;\"\u003eLow molecular weight collagen that reaches the viable epidermis to support the natural collagen matrix\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; text-align: center;\"\u003eEngineered for depth — most collagen in skincare is too large to penetrate\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; font-weight: 600;\"\u003eGreen Algae Extract\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd;\"\u003eStimulates glycosaminoglycan synthesis, supporting skin plumpness and structure\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; text-align: center;\"\u003eConcentrated bioactive extract, not dried powdered algae\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; font-weight: 600;\"\u003ePhospholipid Delivery System\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd;\"\u003eBiocompatible carrier for simultaneous delivery of multiple active ingredients\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; text-align: center;\"\u003eSame technology used in Le Serum, adapted for broader spectrum\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch3\u003eWhat Makes This Cosmeceutical-Grade\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003ePenetrating base.\u003c\/strong\u003e The formula is engineered with a delivery system designed to carry active ingredients beyond the stratum corneum to the viable epidermis, where living cells respond.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOregon Tilth certified organic.\u003c\/strong\u003e One of the strictest organic certifications in the United States — achieved at therapeutic active concentrations, which most organic-certified brands cannot maintain.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFDA-registered manufacturing.\u003c\/strong\u003e The facility meets federal standards for drug-licensed production, a higher bar than cosmetic-only manufacturing.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFormulated by PhD scientists.\u003c\/strong\u003e Dr. Volynsky (PhD organic chemistry) and Dr. Libaridian (PhD pharmaceuticals, R.Ph.) with a combined 50+ years of formulation research.\u003c\/p\u003e\n\u003cp\u003e\u003ca href=\"\/pages\/science-v2\"\u003eLearn More About Science\u003c\/a\u003e | \u003ca href=\"\/pages\/about-us\"\u003eAbout our founders\u003c\/a\u003e | \u003ca href=\"\/blogs\/doctor-notes\"\u003eDoctor's Notes blog\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003eWhat S-ence Replaces\u003c\/h2\u003e\n\u003cp\u003eS-ence is not an addition to your routine. It is a replacement for multiple steps — a single product that does the work of a serum, a moisturiser, and a treatment.\u003c\/p\u003e\n\u003cp\u003eThis is not a shortcut. It is a different approach to formulation: instead of distributing active ingredients across multiple bottles with potentially conflicting pH levels and delivery requirements, S-ence combines them in a single phospholipid-based system that determines the release rate and depth for each active independently.\u003c\/p\u003e\n\u003ch2\u003eThe Problem with Multi-Step Routines\u003c\/h2\u003e\n\u003cp\u003eA typical anti-aging routine involves four to six products: cleanser, toner, serum, eye cream, moisturiser, and occasional treatment. Each product has its own pH. Each active ingredient has its own stability requirements. Some ingredients compete for the same skin receptors. Others neutralise each other on contact.\u003c\/p\u003e\n\u003cp\u003eThe result is a routine where the products are often working against each other — and the user is spending more time managing the routine than benefiting from it.\u003c\/p\u003e\n\u003cp\u003eS-ence solves this by engineering a single formula where every active was designed to work with every other active from the start.\u003c\/p\u003e\n\u003ch2\u003eKey Ingredients\u003c\/h2\u003e\n\u003ch3\u003eIngredient Comparison: Conventional vs S-ence\u003c\/h3\u003e\n\u003ctable style=\"width: 100%; max-width: 700px; border-collapse: collapse; margin: 20px 0; font-family: Assistant,Arial,sans-serif; font-size: 14px;\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"background: #1a2b4a; color: #fff;\"\u003e\n\u003cth style=\"padding: 12px; text-align: left; border: 1px solid #ddd;\"\u003eIngredient\u003c\/th\u003e\n\u003cth style=\"padding: 12px; text-align: center; border: 1px solid #ddd; background: #f4f0eb; color: #1a2b4a;\"\u003eConventional Skincare\u003c\/th\u003e\n\u003cth style=\"padding: 12px; text-align: center; border: 1px solid #ddd; background: #c9a84c; color: #fff;\"\u003eS-ence (Cosmeceutical)\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; font-weight: 600;\"\u003eCollagen type\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; text-align: center;\"\u003eHigh MW (too large to penetrate)\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; text-align: center; font-weight: 600;\"\u003eMicrocollagen — low MW (reaches viable epidermis)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; font-weight: 600;\"\u003eDelivery vehicle\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; text-align: center;\"\u003eStandard cream base\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; text-align: center;\"\u003ePhospholipid carrier\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; font-weight: 600;\"\u003eAlgae ingredient\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; text-align: center;\"\u003eDried or powdered (minimal bioactivity)\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; text-align: center;\"\u003eGreen Algae extract (stimulates GAG synthesis)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background: #f9f9f9;\"\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; font-weight: 600;\"\u003eDevelopment\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; text-align: center;\"\u003e6-12 months\u003c\/td\u003e\n\u003ctd style=\"padding: 10px; border: 1px solid #ddd; text-align: center;\"\u003e5 years\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0828\/2328\/3008\/files\/mdc_s_ence_delivery_e096a3fe-95e9-47ef-9078-012105defb3b.png?v=1779926164\" alt=\"Phospholipid delivery diagram\" style=\"width: 100%; max-width: 700px; margin: 10px 0;\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMicrocollagen\u003c\/strong\u003e — collagen at a molecular weight small enough to penetrate the stratum corneum and reach the viable epidermis, where it supports the skin's natural collagen matrix. Most collagen in skincare is too large to penetrate; it sits on the surface and hydrates. Microcollagen is engineered for depth.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eGreen Algae Extract\u003c\/strong\u003e — stimulates glycosaminoglycan synthesis, supporting the skin's natural plumpness and structure. It also stabilises the collagen stimulation response, preventing the overstimulation that can occur when collagen-supporting ingredients are used in isolation.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePeptide Complex\u003c\/strong\u003e — provides the signalling molecules that tell skin cells to maintain their function, supporting texture, firmness, and resilience over time.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePhospholipid Delivery System\u003c\/strong\u003e — the same technology used in Le Serum, adapted for a broader spectrum of actives. Phospholipids are biocompatible — they are the same class of molecules that make up human cell membranes — allowing them to ferry active ingredients across biological barriers without triggering an immune response.\u003c\/p\u003e\n\u003ch2\u003eThe Development\u003c\/h2\u003e\n\u003cp\u003eS-ence took five years. The challenge was not formulating the individual ingredients — each of microcollagen, green algae extract, and the peptide complex is well-characterised on its own. The challenge was making all of them work simultaneously in an organic-certified base, at therapeutic concentrations, with clinical stability, in a single product that replaces four to six separate bottles.\u003c\/p\u003e\n\u003ch2\u003eThe Economics\u003c\/h2\u003e\n\u003cp\u003eA typical premium anti-aging regimen costs $200–$400 per month when you add up serum, moisturiser, eye cream, and treatment products. S-ence costs significantly less than the sum of products it replaces — because one formula costs less to develop, manufacture, and package than four.\u003c\/p\u003e\n\u003ch2\u003eUsage\u003c\/h2\u003e\n\u003cp\u003eApply a small amount to clean, dry skin morning and evening. Use over the entire face, neck, and décolletage. No additional serum, moisturiser, or treatment needed. Follow with SPF in the morning.\u003c\/p\u003e\n\u003ch2\u003eComparison\u003c\/h2\u003e\n\u003cp\u003eUltra-luxe prestige skincare luxury brands charge $385 for a single cream formulated around a proprietary fermentation technology. S-ence has comparable formulation complexity — multiple active ingredients, a bioavailable delivery system, organic certification, five years of development — at a fraction of the price. The formulation budget is allocated to ingredient concentration and delivery technology, not advertising.\u003c\/p\u003e\n\u003ch2\u003eSuitable For\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSimplified anti-aging routines — one product instead of four to six\u003c\/li\u003e\n\u003cli\u003eMature skin needing broad-spectrum multi-active support\u003c\/li\u003e\n\u003cli\u003eThose who prefer a single-step day\/night product for consistency\u003c\/li\u003e\n\u003cli\u003eTravel and low-maintenance routines\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"Nujevi","offers":[{"title":"1 oz (30 g)","offer_id":48495156855104,"sku":"898225002578","price":190.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0828\/2328\/3008\/files\/mdcosmetique-nujevi-sence.webp?v=1715722134"}],"url":"https:\/\/mdcosmetique.com\/collections\/dry-dehydrated-skin.oembed","provider":"MD Cosmetique","version":"1.0","type":"link"}